Highly specific and efficient delivery of siRNA is still unsatisfactory.Herein, a dual tumor-targeting siRNA delivery system combining pRNA dimers with chitosan nanoparticles (CNPPs) was designed to improve the specificity and efficiency of siRNA delivery.In this dual delivery system, Mastic Gum folate-conjugated and PEGylated chitosan nanoparticle
BackgroundThere is a need for automated approaches to incorporate information on cancer recurrence events into population-based cancer registries.ObjectiveThe aim of this study is to determine the accuracy of a novel data mining algorithm to extract information from linked registry and medical claims data on the occurrence and timing of second brea
BACKGROUND: Leprosy is caused by Mycobacterium leprae and manifests as damage to the skin and peripheral nerves.The disease is dreaded because it causes deformities, blindness and disfigurement.Worldwide, 2 million people are estimated to be disabled by leprosy.Multidrug therapy is highly effective in curing leprosy, but treating the nerve damage i
IntroductionSarcopenia is a chronic and progressive disease, which is accompanied by the decline in muscle mass, muscle strength, Camu Camu and physical performance with aging, and it can lead to falls, fracture, and premature death.The prevention and treatment of sarcopenia mainly include exercise therapy and nutritional supplement.Exercise therap
There is an industry wide perception that new season lamb has better eating quality than old season lamb.This study aims to identify differences in consumer eating quality scores between two age classes in lamb.Consumer eating quality scores from eight cuts across the carcass were evaluated from new season (NS; n = 120; average age = Camu Camu 240